Is there a way to make a day/night cycle (can be just light on/off) with a very high amount of lights?

So, my game is based on a randomly generated Ikea store (Google SCP-3008 for the backstory) and there’s a day/night cycle where all lights are switched off at night.

The problem: Both disabling the lights or using LayerMasks would mean that I’d need to change the value for hundreds of objects.

Is there anything I could modify that is scene-wide, independent from all single lights/objects?

Not sure if this will solve your problem, but you could put all of the lights under one gameobject, and then just disable that object.