Change BuildSettings before run Unit test in Play Mode

I need to create different builds of the project I'm working on.

My builds differs one from the other from some scenes. So I need to change them for each build.

The point is that I woud like to test some workflows of my project with the different builds settings. I've tryed something like this:

 using NUnit.Framework;
 using UnityEditor;
 
 namespace Tests
 {
     public class TestRunner 
     {
         private string oldScenePath;
 
         [SetUp]
         public override void Setup()
         {
             EditorBuildSettingsScene[] newScenes = EditorBuildSettings.scenes;
             oldScenePath = newScenes[3].path;
             newScenes[3].path = "scene/to/change.unity";
             EditorBuildSettings.scenes = newScenes;
         }
 
         [TearDown]
         public override void Teardown()
         {
             EditorBuildSettingsScene[] newScenes = EditorBuildSettings.scenes;
             newScenes[3].path = oldScenePath;
             EditorBuildSettings.scenes = newScenes;
 
         }
 
         [UnityTest]
         public override string Test()
         {
             //Make things
         }
     }
 }

But this does not work, because SetUp is run during running mode, where I can not modify the EditorBuildSettings.

Any advice? Is it possible to make run a script before Unity enters in Play mode before running all the tests?