Nested Prefab built from script SpriteRenderer breaks on Run.

Hello and thanks so much for taking the time to read this post. I am creating a script that will assemble a large image that has been split into smaller images as a nested prefab where the smaller tiles are parented to a container object. This is part of a level editor. Everything is working correctly in editor mode but when I enter game mode all of the sprites turn white. In the inspector, everything looks normal the sprite displays correctly in the inspector. After returning to editor mode the sprites remain white and the prefab itself is now corrupted i.e. new instances of the prefab are also white. In the inspector the only change that I can see is that the Drawmode property is now grayed out. I created a little script to access the DrawMode enum and it displays correctly in the scripts inspector. Currently, my best guess is that there is something about the way that my script is creating the prefab that is incorrect I have included that part of my code here.

 public static class CompositionUtils
 {
     public static GameObject BuildComposition(List<Texture2D> TileTextures, List<Vector2Int> TileCoords, string RootPath, string Name, int Rows, int Cols)
     {
         List<GameObject>CompositionTiles = new List<GameObject>();
         GameObject Parent = new GameObject();
         Sprite sprite;
         SpriteRenderer spriteRenderer;
         string path;
         string spritePath = "/Sprites";
         string tilePath = "/Tiles";
         string compPath = "/" + Name;
         int pxWidth = 0;
         int pxHeight = 0;
         AssetDatabase.CreateFolder(RootPath, Name);
         AssetDatabase.CreateFolder(RootPath + compPath, "Sprites");
         AssetDatabase.CreateFolder(RootPath + compPath, "Tiles");
         float ratio;
         for (int i = 0; i < TileTextures.Count; i++)
         {
             CompositionTiles.Add(new GameObject());
             sprite = Sprite.Create(TileTextures[i], new Rect(0, 0, TileTextures[i].width, TileTextures[i].height), new Vector2(0, 0));
             spriteRenderer = CompositionTiles[i].AddComponent<SpriteRenderer>();
             spriteRenderer.sprite = sprite;
             ratio = spriteRenderer.sprite.pixelsPerUnit;
             pxHeight = TileTextures[i].height;
             pxWidth = TileTextures[i].width;
 
 
             CompositionTiles[i].transform.Translate(new Vector3(TileCoords[i].x * (pxWidth / ratio), ((Rows - 1) * pxHeight / ratio) - TileCoords[i].y * (pxHeight / ratio), 0));
             CompositionTiles[i].transform.SetParent(Parent.transform);
 
            
             
         }
         for (int i = 0; i < CompositionTiles.Count; i++)
         {
             AssetDatabase.CreateAsset(CompositionTiles[i].GetComponent<SpriteRenderer>().sprite, RootPath + compPath + spritePath + "/" + "Sprite" + i + ".asset");
             path = RootPath + compPath + tilePath + "/" + Name + i + ".prefab";
             CompositionTiles[i] = PrefabUtility.SaveAsPrefabAsset(CompositionTiles[i], path);
         }
         path = "Assets/Graphics/Prefabs/" + Name + "/" + Name + ".prefab";
         GameObject CompPrefab = PrefabUtility.SaveAsPrefabAsset(Parent, path);
         MonoBehaviour.DestroyImmediate(Parent);
         return CompPrefab;
        
     }
 }