Inventory and Items

What would be the best practice on making an inventory and item system.

A couple ways I was t$$anonymous$$nking of doing t$$anonymous$$s:

Use scriptable objects for items to store data.
Have an inventory that stores a reference to the scriptable object instead of copying data to a class version of the items scriptable object.
A problem with saving a reference is if you move the items location, then it may not be able to load it back in.

Same way of doing items above, but instead making separate serializable classes to store the data in to that it can be saved. You can also save a location for the object so that you can run a script on load to update any information about the object. Again t$$anonymous$$s would have the same issue when moving objects around in files.

What is the best way to go about doing an inventory and items system?