How to build scene like this?

Hi all!
I want to create my own jRPG game. Probably I will use sprite graphics, but I have no idea how to build a scene like in the screenshots (this is just an example and my game will not use the design elements or the game story of game from screenshots).
In one side, for the sprite graphics I can use the 2d toolkit or any other framework for working with two-dimensional graphics, but in other side, these scenes are built like 3d.

thx!

13886-1.jpg

13887-2.png

Attach some normal 2D Textures to some plane/cubes and then add some collider boxes above and make the camera face down?