can i use makehuman models?

i have created a makehumsn model and inported it into blender and before i textre it and everything i was wondering will this work in unity and if so is there anything i have to do to the model to make it game ready because i have heard it wont work because of high poly and lastly can i lip sync the character

Yes, you can use it unity. The highpoly thing is that if it is too high-poly (too many triangles) it will slow the game down. It should work, and you can do pretty much everything with it.

You're character can't have more triangles than 60.000 - don't forget that