How to avoid hotkey conflicts with unity editor

I'm currently working on an in game level editor and I'm trying to implement a bunch of hotkeys. The problem is that when I try running the game in the editor, almost all the hot keys have a function in the unity editor itself and the editor responds to the commands. Is there a way of telling unity to ignore these while running? For example, I've added an undo function to my level editor and would like to use control-z as every other program uses, but whenever I use it, the unity editor undoes its last change as well.