Box Collider 2d don't collide

Not sure if this will help with your problem but it is worth a try :

http://docs.unity3d.com/ScriptReference/Rigidbody.WakeUp.html

I'm laugting here $$anonymous$$rSoad, I tested what you said, It dont worked but I found the problem, Unity is not recognizing Rigidbody2D check this error message when I add the WakeUp: $$anonymous$$issingComponentException: There is no 'Rigidbody' attached to the "box" game object, but a script is trying to access it. You probably need to add a Rigidbody to the game object "box". Or your script needs to check if the component is attached before using it.

Should have given you this link rather than the one above, the one above if for 3D not 2D. Give this a try :

http://docs.unity3d.com/ScriptReference/Rigidbody2D.WakeUp.html

Another weird thing, If I put gravity scale 0.1 on Rigidbody 2D it works, Its like "Object is too fast at normal speed" The normal gravity Scale is 1

What is your actual scale, put a std Unity cude (3D) in your scene. If it looks huge then you have your whole scale far to small. The cube is 1m in diameter but the physics engine does not like it when small things are modeled at their real life size (a pool table and balls will not work well at the correct real life scale). So it is best to try and have your main objects, player etc, at around the size of the std Unity cube.